Myo-Inositol & D-Chiro Inositol | Hormone Balance for Women | Ideal 40:1 Ratio | Myo Inositol 2000mg, D Chiro 50mg | Vitamin B8 to Regulate Menstrual Cycle & Support Ovarian Health | SM Nutrition

£9.9
FREE Shipping

Myo-Inositol & D-Chiro Inositol | Hormone Balance for Women | Ideal 40:1 Ratio | Myo Inositol 2000mg, D Chiro 50mg | Vitamin B8 to Regulate Menstrual Cycle & Support Ovarian Health | SM Nutrition

Myo-Inositol & D-Chiro Inositol | Hormone Balance for Women | Ideal 40:1 Ratio | Myo Inositol 2000mg, D Chiro 50mg | Vitamin B8 to Regulate Menstrual Cycle & Support Ovarian Health | SM Nutrition

RRP: £99
Price: £9.9
£9.9 FREE Shipping

In stock

We accept the following payment methods

Description

This event is explainable since the DCI-IPG second messenger serves as the signal transduction system for the stimulation—due to insulin—of human testosterone biosynthesis in theca cells [ 38]. Supplement with this 40:1 ratio has been shown to be more effective than either form of inositol alone. They used four concentrations of DCI, namely, 1, 5, 10, and 20 nM: the first one was totally ineffective, 5 nM exerted a barely visible inhibitory activity, whereas 10 and 20 nM achieved a significant inhibitory effect that became greater with increasing DCI concentrations (slightly more than 50% reduction with 20 nM DCI). Furthermore, it was demonstrated that DCI activity is beneficial mainly in a specific ratio with MI, whereas the progressive increase in concentration of DCI causes the parallel loss of the beneficial effects at the reproductive level with concomitant blastocyst quality.

Treatment with inositols has been shown to help improve insulin sensitivity and reduce male hormone levels in females with PCOS. Ovasitol is the first and only 40:1 inositol supplement that’s independently tested and certified by NSF International®, so you know exactly what you’re getting. It means the capsules match the body's ratio of 40:1 Myo-Inositol to D-Chiro Inositol (DCI) which helps with problems like irregular cycles, unwanted hair, and more. realizaron el primer estudio en humanos que comparaba diferentes ratios de MYO/DCI (0:1/1:3,5/2,5:1/5:1/20:1/40:1/80:1), en el que demostraron que la ratio 40:1 era la más efectiva. In 1998, before the study publication, Insmed Pharmaceuticals had obtained a US patent claiming the effectiveness of DCI in the treatment of PCOS and, in 2002, a follow-up study was performed by the same group in lean women with PCOS [ 15].In conclusion, a higher MI/DCI ratio in FF correlated positively with good quality blastocysts, therefore constituting a promising parameter for the success of embryo implantation and pregnancy in IVF patients undergoing intracytoplasmic sperm injection (ICSI). Like SGLT1, the glucose transporter of the small intestine, SMIT2, is sensitive to phlorizin, which acts as a potent inhibitor at an average Ki of 15 ± 6 μM [ 46]. In particular, a slight trend toward testosterone decrease was observed with respect to controls, whereas androstenedione levels remained unchanged. Furthermore, myoinositol and DCI can decrease plasma concentrations of testosterone and LH, and the LH/FSH ratio, thus counteracting the effects of hyperandrogenism and reducing hirsutism and acne.

Indeed, although muscle and liver are insulin resistant in women with PCOS, the ovaries retain normal insulin sensitivity, highlighting the tissue-specificity of insulin resistance in PCOS. Myo + D-Chiro is GMO-free, vegetarian, and is made without gluten, yeast, dairy, artificial colors or preservatives. A combined therapy with myo-inositol and D-chiro-inositol improves endocrine parameters and insulin resistance in PCOS young overweight women. In PCOS women, in addition to the excessive conversion of myo into D-chiro and the lack of myo in the follicles [1], a positive correlation was also found between the volume of the follicular fluid, myo inositol and the presence of mature oocytes. Given this overview of the scientific evidence thus far available regarding inositol pharmacokinetics and pharmacodynamics, we were astonished when we analyzed the current inositol market for the treatment of PCOS as we find a high number of combinations between MI and DCI, often in combination with other molecules (Tables ​ (Tables1 1 and ​ and2).BRING BALANCE TO YOUR BODY: Each serving of our myoinositol pills contains 2000mg of MyoInositol and 50mg of D-chiro inositol. If your healthcare provider agrees and you decide to try inositols, you may need to be extra careful of what you eat and drink. It is for this reason that an increasing number of studies have focused on evaluating the combination of the two inositols as a treatment for PCOS. Myo-inositol administration positively effects ovulation induction and intrauterine insemination in patients with polycystic ovary syndrome: a prospective, controlled, randomized trial.

These observations induce one to think that DCI excess in the ovary stimulates ovarian androgen production and can help to explain the worsening of oocyte and blastocyst quality observed with high DCI levels [ 37].

As with any dietary supplement, discuss with your pharmacist and/or healthcare team to determine whether Ovasitol can be taken along with your medications.



  • Fruugo ID: 258392218-563234582
  • EAN: 764486781913
  • Sold by: Fruugo

Delivery & Returns

Fruugo

Address: UK
All products: Visit Fruugo Shop